李 伟，博士，教授，博士生导师，林木遗传育种全国重点实验室副主任
E-mail：weili2015@nefu.edu.cn
电 话：0451－82191965
研究方向：木材形成与环境适应的分子基础
研究领域：
从事林木遗传改良的分子基础研究，以杨树为材料，重点研究木材形成调控分子机制、林木次生生长与环境适应机制等，并致力于通过分子设计育种培育高产、优质、高抗的林木新品种。
学习经历：
2005/09-2010/07，山东农业大学，生命科学学院，发育生物学，博士
2001/09-2005/07，山东农业大学，生命科学学院，生物技术，学士
工作经历：
2015/08-至今，东北林业大学，林学院林木遗传育种学科，教授、博导
2013/12-2015/07，东北林业大学，林学院林木遗传育种学科，兼职教授
2012/08-2015/07，美国北卡罗来纳州立大学，林木生物技术中心，博士后
2010/07-2012/07，美国明尼苏达大学，生命科学学院植物科学系，博士后
人才计划
曾入选国家“青年海外高层次人才”、国家林草局“科技创新领军人才”、中国科协“青年人才托举工程”、黑龙江省“龙江学者青年学者”等人才计划，并获国家自然科学基金委“优秀青年科学基金”项目资助。
学术兼职
兼任林木分子生物学国家创新联盟秘书长、中国林学会青年工作委员会第四届委员会副主任委员、林木基因组与基因工程国家创新联盟副秘书长、中国林学会林木遗传育种分会第八届委员会常委、中国遗传学会表型组学专业委员会委员、黑龙江省植物学会第三届理事会常务理事等。兼任Journal of Forestry Research编委、Plant Communications树木生物学与生物技术专刊和Frontiers in Plant Science木材发育生理专刊的特约编辑以及《南京林业大学学报》和《木材科学与技术》青年编委等。
科技奖励
获得中国林业青年科技奖、中国遗传学会青年创新奖、黑龙江省高校科学技术奖自然科学奖一等奖、梁希林业科学技术奖自然科学奖二等奖和首届朱之悌奖励基金优秀青年科技奖等奖项。
科研项目
1．木材形成过程中细胞分裂和分化的分子调控机理（2021YFD2200700），“十四五”国家重点研发计划青年科学家项目，负责人，2021－2026。
2．树木次生生长与逆境胁迫平衡的遗传机制（2016YFD0600106），“十三五”国家重点研发计划课题，负责人，2016－2020。
3．林木遗传育种学（31522014），国家自然科学基金优秀青年项目，负责人，2016－2018。
4．组蛋白修饰H3K9ac与转录因子AREB1协同调控毛果杨响应干旱胁迫的分子机制研究（31570663），国家自然科学基金面上项目，负责人，2016－2019。
5．小黑杨木材形成和环境适应性的基因组基础（2572018CL02），中央高校基本科研业务专项资金项目，负责人，2018－2020。
6．构建完整的调控木材发育过程中木质素合成的多级分层转录调控网络（31430093），国家自然科学基金重点项目，主要参加人，2015－2019。
代表性论文
1. Baofeng Zhang, Zhuwen Wang, Xiufang Dai, Jinghui Gao, Jinfeng Zhao, Rong Ma, Yanjie Chen, Yi Sun, Hongyan Ma, Shuang Li, Chenguang Zhou, Jack P. Wang, Wei Li*. A COMPASS histone H3K4 trimethyltransferase pentamer transactivates drought tolerance and growth/biomass production in Populus trichocarpa. New Phytologist, 2024, 241: 1950–1972.
2. Wei Li#, Ying-Chung Jimmy Lin#, Ying-Lan Chen, Chenguang Zhou, Shuang Li, Nette De Ridder, Dyoni M. Oliveira, Lanjun Zhang, Baocai Zhang, Jack P. Wang, Changzheng Xu, Xiaokang Fu, Keming Luo, Ai-Min Wu, Taku Demura, Meng-Zhu Lu, Yihua Zhou, Laigeng Li, Toshiaki Umezawa, Wout Boerjan, Vincent L. Chiang*. Woody plant cell walls: Fundamentals and utilization. Molecular Plant, 2024, 17: 112–140.
3. Xiufang Dai, Rui Zhai, Jiaojiao Lin, Zhifeng Wang, Dekai Meng, Meng Li, Yuli Mao, Boyuan Gao, Hongyan Ma, Baofeng Zhang, Yi Sun, Shuang Li, Chenguang Zhou, Ying-Chung Jimmy Lin, Jack P. Wang, Vincent L. Chiang, Wei Li*. Cell-type-specific PtrWOX4a and PtrVCS2 form a regulatory nexus with a histone modification system for stem cambium development in Populus trichocarpa. Nature Plants, 2023, 9: 96–111.
Highlighted with a News & Views article in Nature Plants, 2023, 9: 7–8.
4. Huizi Liu, Jinghui Gao, Jiatong Sun, Shuang Li, Baofeng Zhang, Zhuwen Wang, Chenguang Zhou, Daniel Barletta Sulis, Jack P. Wang, Vincent L. Chiang, Wei Li*. Dimerization of PtrMYB074 and PtrWRKY19 mediates transcriptional activation of PtrbHLH186 for secondary xylem development in Populus trichocarpa. New Phytologist, 2022, 234: 918–933.
5. Jing Yu, Chenguang Zhou, Danning Li, Ying-Chung Jimmy Lin, Jack P. Wang, Vincent L. Chiang, Wei Li*. A PtrLBD39-mediated transcriptional network regulates tension wood formation in Populus trichocarpa. Plant Communications, 2022, 3: 100250.
6. Zhifeng Wang, Yuli Mao, Yanjiao Guo, Jinghui Gao, Xinying Liu, Shuang Li, Ying-Chung Jimmy Lin, Hao Chen, Jack P. Wang, Vincent L. Chiang, Wei Li*. MYB transcription factor161 mediates feedback regulation of Secondary wall-associated NAC-Domain1 family genes for wood formation. Plant Physiology, 2020, 184: 1389–1406.
Featured on the cover of Plant Physiology, 2020, Vol. 184, Issue 3.
7. Shuang Li, Ying-Chung Jimmy Lin, Pengyu Wang, Baofeng Zhang, Meng Li, Su Chen, Rui Shi, Sermsawat Tunlaya-Anukit, Xinying Liu, Zhifeng Wang, Xiufang Dai, Jing Yu, Chenguang Zhou, Baoguang Liu, Jack P. Wang, Vincent L. Chiang*, Wei Li*. The AREB1 transcription factor influences histone acetylation to regulate drought responses and tolerance in Populus trichocarpa. Plant Cell, 2019, 31: 663–686.
Highlighted with an In Brief article in Plant Cell, 2019, 31: 559–560.
8. Hao Chen, Jack P. Wang, Huizi Liu, Huiyu Li, Ying-Chung Jimmy Lin, Rui Shi, Chenmin Yang, Jinghui Gao, Chenguang Zhou, Quanzi Li, Ronald R. Sederoff, Wei Li*, Vincent L. Chiang*. Hierarchical transcription factor and chromatin binding network for wood formation in Populus trichocarpa. Plant Cell, 2019, 31: 602–626.
Featured on the cover of Plant Cell, 2019, Vol. 31, Issue 3.
Highlighted with Science News in ScienceDaily, March 6, 2019.
9. Chung-Shu Yeh, Zhifeng Wang, Fang Miao, Hongyan Ma, Chung-Ting Kao, Tzu-Shu Hsu, Jhong-He Yu, Er-Tsi Hung, Chia-Chang Lin, Chen-Yu Kuan, Ni-Chiao Tsai, Chenguang Zhou, Guan-Zheng Qu, Jing Jiang, Guifeng Liu, Jack P. Wang, Wei Li*, Vincent L. Chiang*, Tien-Hsien Chang*, Ying-Chung Jimmy Lin*. A novel synthetic-genetic-array based yeast one-hybrid system for high discovery rate and short processing time. Genome Research, 2019, 29: 1343–1351.
10. Meng Li, Hao Dong, Jiyuan Li, Xiufang Dai, Jiaojiao Lin, Shuang Li, Chenguang Zhou, Vincent L. Chiang, Wei Li*. PtrVCS2 regulates drought resistance by changing vessel morphology and stomatal closure in Populus trichocarpa. International Journal of Molecular Sciences, 2023, 24: 4458.
11. Wei Li, Ying-Chung Lin, Quanzi Li, Rui Shi, Chien-Yuan Lin, Hao Chen, Ling Chuang, Guan-Zheng Qu, Ronald R. Sederoff, Vincent L. Chiang*. A robust chromatin immunoprecipitation protocol for studying transcription factor-DNA interactions and histone modifications in wood-forming tissue. Nature Protocols, 2014, 9: 2180–2193.
12. Ying-Chung Lin, Wei Li, Hao Chen, Quanzi Li, Ying-Hsuan Sun, Rui Shi, Chien-Yuan Lin, Jack P. Wang, Hsi-Chuan Chen, Ling Chuang, Guan-Zheng Qu, Ronald R. Sederoff, Vincent L. Chiang*. A simple improved-throughput xylem protoplast system for studying wood formation. Nature Protocols, 2014, 9: 2194–2205.
13. Ying-Chung Lin#, Wei Li#, Ying-Hsuan Sun, Sapna Kumari, Hairong Wei, Quanzi Li, Sermsawat Tunlaya-Anukit, Ronald R. Sederoff, Vincent L. Chiang*. SND1 transcription factor-directed quantitative functional hierarchical genetic regulatory network in wood formation in Populus trichocarpa. Plant Cell, 2013, 25: 4324–4341.
Highlighted with an In Brief article in Plant Cell, 2013, 25: 4282.
14. Baoguang Liu, Juan Liu, Jing Yu, Zhifeng Wang, Yi Sun, Shuang Li, Ying-Chung Jimmy Lin, Vincent L. Chiang, Wei Li, Jack P. Wang*. Transcriptional reprogramming of xylem cell wall biosynthesis in tension wood. Plant Physiology, 2021, 186: 250–269.
Highlighted with News and Views in Plant Physiology, 2021, 186: 212–214.
15. Wei Li, Hui Liu, Zhijuan Cheng, Yinghua Su, Huanan Han, Yan Zhang, Xiansheng Zhang*. DNA methylation and histone modifications regulate de novo shoot regeneration in Arabidopsis by modulating WUSCHEL expression and auxin signaling. PLoS Genet., 2011, 7: e1002243.
专利
1. 毛果杨PtrbHLH186基因在调控树木次生木质部发育中的应用。发明人：李伟，刘慧子，李爽，高境烩，孙佳彤，姜立泉，ZL202111439268.1，发明专利。
2. 毛果杨PtrMIF2基因在调控树木维管形成层发育中的应用。发明人：李伟，代秀芳，李爽，林娇娇，翟睿，姜立泉，202210881406.X，发明专利。
其他
1. 全国林草科技创新人才计划林木分子生物学创新团队骨干成员。
2. 黑龙江省头雁团队林木遗传育种创新研究团队骨干成员。